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Course # 30712 • Multiple Myeloma


This course will review the plasma cell malignancy of multiple myeloma. Diagnostic workup includes a complete history and physical, laboratory testing with an emphasis on blood, immunoglobulins, and urine for abnormal protein tumor markers. Imaging focuses on computerized tomography, magnetic resonance imaging and skeletal surveys. Bone marrow aspiration and biopsy are equally important in establishing the definitive diagnosis of multiple myeloma. To assist in understanding the interaction between plasma cells and bone cells, and the subsequent disease process, normal cell formation and bone marrow function will be reviewed. Treatment plans vary depending on the inevitable drug resistance and disease progression. Chemotherapy, glucocorticoids, radiation, stem cell transplantations, immunomodulators, proteasome inhibitors and bisphosphonates are included for discussion. The goal of treatment with multiple myeloma is to prolong overall survival and control the disease activity. These goals require patient and family education to begin from the time the diagnosis is established. Measures to recognize, treat, and avoid potential side effects from prescribed therapies and complications from the disease progression are paramount to patient care. Maintaining an optimal level of functioning and promoting quality of life are synonymous with pain control and achieving the goal of making every day a good one.

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Education Category: Medical / Surgical

Release Date: 04/01/2018

Expiration Date: 03/31/2021


This course is designed for nurses and allied healthcare professionals involved in the care, treatment, and education of patients with the diagnosis of multiple myeloma.


In support of improving patient care, NetCE is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. NetCE is approved to offer continuing education through the Florida Board of Nursing Home Administrators, Provider #50-2405. NetCE is approved by the California Nursing Home Administrator Program as a provider of continuing education. Provider number 1622. NetCE is accredited by the International Association for Continuing Education and Training (IACET). NetCE complies with the ANSI/IACET Standard, which is recognized internationally as a standard of excellence in instructional practices. As a result of this accreditation, NetCE is authorized to issue the IACET CEU.

Designations of Credit

NetCE designates this continuing education activity for 10 ANCC contact hour(s). NetCE designates this continuing education activity for 4 pharmacotherapeutic/pharmacology contact hour(s). NetCE designates this continuing education activity for 12 hours for Alabama nurses. This home study course is approved by the Florida Board of Nursing Home Administrators for 5 credit hour(s). This course is approved by the California Nursing Home Administrator Program for 10 hour(s) of continuing education credit - NHAP#1622010-7137/P. California NHAs may only obtain a maximum of 10 hours per course. NetCE is authorized by IACET to offer 1 CEU(s) for this program. AACN Synergy CERP Category A.

Individual State Nursing Approvals

In addition to states that accept ANCC, NetCE is approved as a provider of continuing education in nursing by: Alabama, Provider #ABNP0353, (valid through November 21, 2021); Arkansas, Provider #50-2405; California, BRN Provider #CEP9784; California, LVN Provider #V10662; California, PT Provider #V10842; District of Columbia, Provider #50-2405; Florida, Provider #50-2405; Georgia, Provider #50-2405; Kentucky, Provider #7-0054 through 12/31/2021; South Carolina, Provider #50-2405. South Carolina, Provider #50-2405; West Virginia RN and APRN, Provider #50-2405.

Course Objective

Multiple myeloma is the second most prevalent hematologic cancer after non-Hodgkin lymphoma. While great strides have been made to improve survival rates with this disease, and positive outcomes have been attained over the last ten years, multiple myeloma remains an incurable disease. The purpose of this course is to provide healthcare professionals in contact with multiple myeloma patients the information necessary to provide optimum care, treatment, and patient education.

Learning Objectives

Upon completion of this course, you should be able to:

  1. Review the history of multiple myeloma.
  2. Describe the pathophysiology and differentiation of multiple myeloma.
  3. Discuss the etiology, epidemiology, and clinical presentation of multiple myeloma.
  4. Review multiple myeloma-associated physiology, including normal plasma cell formation, the significance of immunoglobulins, and bone homeostasis.
  5. Discuss the diagnostic workup associated with multiple myeloma.
  6. Describe the staging of multiple myeloma with prognostic indicators.
  7. Discuss the role of glucocorticoids and bisphosphonates in the treatment of patients with multiple myeloma, incorporating regimens for relapsed/refractory disease with recognition of anticipated side effects.
  8. Outline the role and action of the immuno-modulators in the treatment of multiple myeloma, including side effects and patient education.
  9. Discuss stem cell transplantation as a treatment option for multiple myeloma.
  10. Discuss disease-related complications and potential oncologic emergencies associated with multiple myeloma, including interventions and treatment.


Jacqueline Houtman, RN, MA, CDP, graduated with an Associate's degree from the Eastbourne School of Nursing in England in 1971. In 2000, she graduated with a Master's degree in Applied Social Science from Binghamton University, Upstate New York. During the course of her nursing career, Ms. Houtman has held various positions in the acute care hospital setting, including medical, surgical, orthopedic, ophthalmic, and intensive care units, incorporating five years of case management.

Faculty Disclosure

Contributing faculty, Jacqueline Houtman, RN, MA, CDP, has disclosed no relevant financial relationship with any product manufacturer or service provider mentioned.

Division Planner

Jane C. Norman, RN, MSN, CNE, PhD

Division Planner Disclosure

The division planner has disclosed no relevant financial relationship with any product manufacturer or service provider mentioned.

About the Sponsor

The purpose of NetCE is to provide challenging curricula to assist healthcare professionals to raise their levels of expertise while fulfilling their continuing education requirements, thereby improving the quality of healthcare.

Our contributing faculty members have taken care to ensure that the information and recommendations are accurate and compatible with the standards generally accepted at the time of publication. The publisher disclaims any liability, loss or damage incurred as a consequence, directly or indirectly, of the use and application of any of the contents. Participants are cautioned about the potential risk of using limited knowledge when integrating new techniques into practice.

Disclosure Statement

It is the policy of NetCE not to accept commercial support. Furthermore, commercial interests are prohibited from distributing or providing access to this activity to learners.

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